閉塞(へいそく)

blockage; obstruction; closure

閉塞感(へいそくかん)

feeling of confinement; sense of being stifled

要塞(ようさい)

fortress; stronghold

塞(ふさ)ぎ込(こ)む

to become depressed; to shut oneself away

塞(せ)き止(と)める

to block; to stop the flow of

塞(ふさ)がる

to be blocked; to be closed

立(た)ち塞(ふさ)がる

to stand in the way; to block

血管(けっかん)が詰(つ)まり、脳梗塞(のうこうそく)を起(お)こした。

A blood vessel became blocked, causing a cerebral infarction.

彼(かれ)は失敗(しっぱい)してから、塞(ふさ)ぎ込(こ)むようになった。

After the failure, he became withdrawn.